Q-Sense develops and markets research instruments based on Quartz Crystal Microbalance (QCM) with Dissipation monitoring (QCM-D) technology.



products are suitable for studying molecular interactions and surface science, providing answers about mass and structural changes at the nanoscale level.


The QCM is based on a vibrating quartz crystal sensor (an acoustic resonator); then measurements are made of  changes in vibration frequency in response to reactions that occur on the sensor surface. Since 1999, when the first commercial QCM-D (trademarked)  instrument was created, Q-Sense has become the worlds leading supplier of acoustic resonator-based instruments. It is used in interfacial acoustic sensing. Its most common application is the determination of a film thickness in a liquid environment (such as the thickness of an adsorbed protein layer). It can be used to investigate further properties of the sample, most notably the layer’s softness.

Being a QCM, the QCM-D works in real-time, does not need labeling, and is surface-sensitive.

Q-Sense instruments are found in over 25 countries worldwide and there are currently over 750 publications citing the use of the QCM-D technology.

 Qsense QCM-D Omega



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Products Technologies
Q-Sense pro QCM-D technology
Q-Sense Analyser Modules & Sensor accessories
Q-Sense Explorer
Q-Sense Initiator


Q-Sense was founded in 1996 by a group of researchers at the Department of Applied Physics, Chalmers University of Technology in Gothenburg, Sweden. There, QCM-related research had been ongoing since the 1970s. The research group discovered and patented (in 1995) a whole new way of extracting mass and viscosity parameters for surface analysis in liquid, based on analyzing the dissipationof the oscillating sensor. The new technique was called QCM-D (Quartz Crystal Microbalance with Dissipation monitoring). By measuring both the dissipation (D) factor and the frequency (f), it became possible to analyze the entire chain of reactions that occur when a new substance is introduced to the surface of the quartz crystal.

At the beginning of 1998, the company began to develop its first commercial product, which resulted in the Q-Sense D300 system, the world’s first multi-frequency QCM-D instrument measuring the viscoelastic properties of adsorbing layers in liquid. This product has now been replaced with the second generation system on the market, the Q-Sense E-series.

Q-Sense started as a self-contained company in Gothenburg, Sweden. Today, Q-Sense is a business unit within Biolin Scientific AB with subsidiaries in the U.S. and Asia, and a well-established distributor network in Europe and Asia